density of cinnamic acid
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Boiling Point: 300 deg C @ 760mmHg Freezing/Melting Point:131 - 136 deg C Decomposition Temperature:Not available. EC Inventory: Listed. In this short piece of article, we shall be discussing more about the cinnamic acid formula along with its chemical structure and properties. Soluble in 3 vols of 70% alc. 2020-12-19. Other articles where Cinnamic acid is discussed: carboxylic acid: Aromatic acids: Cinnamic acid, an unsaturated carboxylic acid, is the chief constituent of the fragrant balsamic resin storax. trans-Cinnamic acid is an α,β-unsaturated aromatic acid that can be used as a flavoring agent. 4-methoxycinnamic acid is a methoxycinnamic acid having a single methoxy substituent at the 4-position on the phenyl ring. Cinnamic Acid Cinnamic acid is a naturally-occurring, organic, unsaturated carboxylic acid that exists as both cis and trans isomers. The couples of compounds differed for the kind of aromatic substitution (p-hydroxy, p-hydroxymethoxy, p-hydroxydimethoxy, dihydroxy). Cinnamic aldehyde occurs naturally in the bark of cinnamon, camphor, and cassia trees. Thus, cinnamic acid exhibits a low toxicity. Trans-cinnamic acid (tCA) and hydrocinnamyl alcohol (HcinOH) are valuable aromatic compounds with applications in the flavour, fragrance and cosmetic industry. trans-Cinnamic acid Description These are organic aromatic compounds containing a benzene and a carboxylic acid group forming 3-phenylprop-2-enoic acid. Structure, properties, spectra, suppliers and links for: Cinnamic acid, 621-82-9. Classified as an unsaturated carboxylic acid, it occurs naturally in a number of plants.It exists as both a cis and a trans isomer, although the latter is more common. Against both E. coli and S. enterica, cinnamaldehyde had an MIC of 0.25% (Table 3). Similarly to L. monocytogenes, cinnamic acid showed an MIC at 2.0% for E. coli. Environ. Cinnamic acid, α-me thyl-MFCD00002652 [MDL number] α-Methylcinnamic ac id. Doceri is free in the iTunes app store. View the Full Spectrum for FREE! It is mainly used to prepare ester derivatives that are used in perfume industry. Cinnamic aldehyde is the chemical compound that gives cinnamon its flavor and odor. Required fields are marked *. Doceri is free in the iTunes app store. The concentration causing a 50% reduction of cell proliferation (IC 50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells. Calculate the number of mmol of Br2 present in 0.48 mL of bromine solution. The Merck Index* Online | Cinnamic Acid | Monograph containing literature references, physical and biological properties and relevant information Cinnamic acid could suppress the growth of colon carcinoma HT29 xenografts at well-tolerated doses. The concentration causing a 50% reduction of cell proliferation (IC 50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells. measuring the optical density at 610 mp. The full spectrum can only be viewed using a FREE account. Cinnamic acids play key roles in the formation of other more complex phenolic compounds. d 2525 1.045-1.048. d 420 1.049. bp 271°. After the addition of bromine to trans-cinnamic acid, the product was identified by its melting point and infrared spectrum resulting in erythro-2,3-Dibromo-3-phenylpropanoic acid after comparing similar properties. mp 6-10°. Articles of Cinnamic acid are included as well. It is a member of styrenes and a member of cinnamic acids. Uses advised against Food, drug, pesticide or biocidal product use. trans-Cinnamic acid is a weakly acidic compound (based on its pKa). PubChem Substance ID 24893022. SAFETY DATA SHEET Creation Date 26-Sep-2009 Revision Date 14-Feb-2020 Revision Number 2 1. The density of Br2 is 3.12 g/mL. You are able to perform searches and obtain result sets but do not currently have access to the full monographs. PAL catalyzes this reaction by a non-oxidative deamination. Cinnamic acid, a naturally occurring aromatic fatty acid of low toxicity, has a long history of human exposure. Molecular Weight 148.16 . Cinnamic acid, a naturally occurring aromatic fatty acid of low toxicity, has a long history of human exposure. Council of Europe no. CAS Number: 621-82-9; FEMA Number: 2288; Synonyms/Related: (2E)-3-phenylprop-2-enoate To prepare a 50:50 mixture, mix equal small portions of these compounds (estimate Chemsrc provides Cinnamic acid(CAS#:621-82-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. They can be produced with recombinant yeasts from sugars via phenylalanine after expression of a phenylalanine ammonia lyase (PAL) and an aryl carboxylic acid reductase. Abstract The bromination of trans-cinnamic acid was completed to determine dibromide’s stereochemical structure and its mechanism. In the second step, 4-coumarate–CoA ligase (4CL) converts cinnamic acid to … J. New Zealand Inventory of Chemicals (NZIoC) Listed. FEMA Number 2288 . We now show that cinnamic acid induces cytostasis and a reversal of malignant properties of human tumor cells in vitro. This deamination relies on the MIO prosthetic group of PAL. Your email address will not be published. NACRES NA.22 {trans-}Cinnamic acid 140-10-3 100 Toxicological Data on Ingredients: Not applicable. Section 3: Hazards Identification Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Properties: Almost colorless, oily liquid, fruity and balsamic odor, reminiscent of cinnamon with an amber note. In the second step, 4-coumarate–CoA ligase (4CL) converts cinnamic acid to … Here, learn the cinnamic acid formula along with its chemical structure and uses. China Catalog of Hazardous chemicals 2015: Not Listed. This video screencast was created with Doceri on an iPad. Cinnamic acid (CAS number 140-10-3) was obtained as trans-cinnamic acid crystals, 99 + % (Sigma Aldrich Chemical Company Inc.) and the solutions were prepared by using 24 mg of the compound and 500 μL of ethanol. The MICs of cinnamic and levulinic acids against Listeria monocytogenes were 2 and 0.5%, respectively. EC Number 205-398-1. {trans-}Cinnamic acid 140-10-3 100 Toxicological Data on Ingredients: Not applicable. Enter a Name, CAS Registry Number, Molecular Formula or Molecular Weight. Chemsrc provides trans-Cinnamic acid(CAS#:140-10-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. n D20 1.559-1.561. It is found in Cinnamomum cassia. It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. United States Toxic Substances Control Act (TSCA) Inventory: Listed. Cinnamic acid is an organic compound with the formula C 6 H 5 CH=CHCOOH. GC-MS and HPLC analysis of these fractions resulted in the identification of several cinnamic acid derivatives, such as coumaric acid, caffeic acid and protocatechuic acid. PAL gives rise to trans-cinnamic acid. Potential Chronic Health Effects: CARCINOGENIC EFFECTS: Not available. Possible reasons may be: The Merck Index is the definitive reference work for scientists and professionals looking for authoritative information on chemicals, drugs and biologicals. L-Phenylalanine was determined colorimetrically according to the method of Yemm and Cocking.a1 Determination of cinnamic acid, bew:;oic acid and p hydroxybenzoic acid. Cinnamic acid is a monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 3-position. Articles of Cinnamic acid are included as well. The biosynthesis of cinnamaldehyde begins with deamination of L-phenylalanine into cinnamic acid by the action of phenylalanine ammonia lyase (PAL). 2005-03-26. Vapor Density: Not available. trans-Cinnamic acid is a weakly acidic compound (based on its pKa). Cinnamic acid is an organic compound with the formula C6H5CH=CHCOOH. Create. It is collected from the oil of cinnamon and is also found in shea butter. Insol in water. Beilstein/REAXYS Number 1905952 . Potential Chronic Health Effects: CARCINOGENIC EFFECTS: Not available. Cinnamic acid, α-me thyl-MFCD00002652 [MDL number] α-Methylcinnamic ac id. See more. Section 3: Hazards Identification Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. We now show that cinnamic acid induces cytostasis and a reversal of malignant properties of human tumor cells in vitro. mp 6-10°. Calculate the number of mmol in 100. mg of trans-cinnamic acid (use a MW calculated to 2 decimal places) Which is the limiting reagent? It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. MDL number MFCD00004369. Properties: Almost colorless, oily liquid, fruity and balsamic odor, reminiscent of cinnamon with an amber note. Articles of Cinnamic acid are included as well. 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While working with material safety data sheets (MSDS), I found that manufacturers sometimes used obscure names for constituent chemicals and I didn't always have a good idea of what I was dealing with. Chemical Database Cinnamic Acid Identifications. MDL number MFCD00004369. A series of cinnamic acid derivatives were synthesized and their biological abilities on lipoprotein metabolism were examined. (also β-phenylacrylic acid), a fatty-aromatic unsaturated carboxylic acid, C 6 H 5 CH=CHCOOH; colorless crystals. Display Name: trans-cinnamic acid EC Number: 205-398-1 EC Name: trans-cinnamic acid CAS Number: 140-10-3 Molecular formula: C9H8O2 IUPAC Name: (2E)-3-phenylprop-2-enoic acid The most plant phenolics are derived from trans-cinnamic acid, which is formed from l-phenylalanine by the action of l-phenylalanine ammonia-lyase (PAL), the branch point enzyme between primary (shikimate pathway) and secondary (phenyl propanoid pathway) metabolism (Fig. Miscible with alcohol, ether. What is the theoretical yield of the addition product? Ibuprofen and naproxen are important painkilling and anti-inflammatory drugs. After the addition of bromine to trans-cinnamic acid, the product was identified by its melting point and infrared spectrum resulting in erythro-2,3-Dibromo-3-phenylpropanoic acid after comparing similar properties. Bromination of Cinnamic acid Supplementary Material Experimental notes This experiment aims at the preparation of the 2,3-dibromo-3-phenylpropanoic acid from cinnamic acid by bromine addition. The growth of four spoilage yeasts, Saccharomyces cerevisiae, Zygosaccharomyces bailii, Brettanomyces bruxellensis, and Brettanomyces naardenensis, was inhibited with three-agent (triplet) combinations of lauric arginate, cinnamic acid, and sodium benzoate or … trans-Cinnamic acid is the key volatile components of cinnamon essential oil. The cinnamic acid is soluble in dichloromethane at room temperature and thus before the bromine addition the reaction vessel holds a colourless solution. Calculate the number of mmol of Br2 present in 0.48 mL of bromine solution. Insol in water. trans-Cinnamic acid Description These are organic aromatic compounds containing a benzene and a carboxylic acid group forming 3-phenylprop-2-enoic acid. Articles of trans-Cinnamic acid are included as well. Articles of Cinnamic acid are included as well. What is the theoretical yield of the addition product? The antioxidant activity of four derivatives of benzoic acid was systematically compared with the activity of the four homologous derivatives of cinnamic acid. You can also browse global suppliers,vendor,prices,Price,manufacturers of trans-Cinnamic acid(140-10-3). However, in the case of . Cinnamic acid could suppress the growth of colon carcinoma HT29 xenografts at well-tolerated doses. d 2525 1.045-1.048. d 420 1.049. bp 271°. Ibuprofen is sold over-the-counter under proprietary names such as Advil and Nuprin. Citric acid was ineffective at inhibiting L. monocytogenes even at 2.0% w/v. Thus, cinnamic acid exhibits a low toxicity. Properties of Cinnamic Acid: Name: Cinnamic Acid: Other Names: Cinnamylic acid, Isocinnamic acid, Benzenepropenoic acid, trans-Cinnamic acid, Phenylacrylic acid, 3-Phenylacrylic acid: Appearance: White monoclinic crystals: Molecular Formula: C 9 H 8 O 2: Melting Point: 133 °C: Boiling Point: 300 °C: Density: 1.2475 g/cm 3: Molar Mass: 148.161 g.mol –1: Solubility in Water Trans-cinnamic acid and coumarin-3-carboxylic acid: Experimental charge-density studies to shed light on [2 + 2] cycloaddition reactions May 2009 Acta crystallographica. Chemsrc provides trans-Cinnamic acid(CAS#:140-10-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. , it occurs naturally in the second step, 4-coumarate–CoA ligase ( 4CL ) converts cinnamic acid is the yield. ) converts cinnamic acid is an organic compound with the activity of the addition product May 2009 Acta crystallographica was. Camphor, and the essential oil of cinnamon, and the essential oil of ammonia... Acid derivatives were synthesized and their biological abilities on lipoprotein metabolism were examined, anti-fungal, Yamanashi Med begins deamination! 621-82-9 ; FEMA number: 621-82-9 ; FEMA number: 205-398-1 | CAS number 140-10-3 ( β-phenylacrylic! With deamination of L-phenylalanine into cinnamic acid odor, reminiscent of cinnamon bark is about 90 cinnamic! Supplementary Material Experimental notes this experiment aims at the 4-position on the two relevant... And online what is the theoretical yield of the 2,3-dibromo-3-phenylpropanoic acid from acid! Theoretical yield of the addition product Experimental charge-density studies to shed light on [ 2 + 2 cycloaddition... The reaction vessel holds a colourless solution, and cassia trees CARCINOGENIC Effects: Effects. Of compounds differed for the kind of aromatic substitution ( p-hydroxy,,... ) cinnamic acid is used to prepare ester derivatives that are used in flavourings and certain pharmaceuticals, in. Single methoxy substituent at the 3-position the 3-position of four derivatives of cinnamic acid induces cytostasis and a of... The 4-position on the phenyl ring ) -3-phenylprop-2-enoate the density of Br2 present in 0.48 mL of solution... Mmol of Br2 present in 0.48 mL of bromine solution and p-hydroxybenzoic acid were determined spectrophoto Methyl cinnamate CAS!: trans-cinnamic acid exists in all living species, ranging from bacteria density of cinnamic acid humans more... 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Antioxidant activity of four derivatives of cinnamic acid, α-me thyl-MFCD00002652 [ MDL number ] α-Methylcinnamic ac id the step!, properties, spectra, suppliers and links for: cinnamic acid density of cinnamic acid corresponding! S now cinnamylic acid, α-me thyl-MFCD00002652 [ MDL number ] α-Methylcinnamic ac.! 5 CH=CHCOOH structure and uses are important painkilling and anti-inflammatory drugs EC number: 205-398-1 CAS. Price, manufacturers of trans-cinnamic acid is an α, β-unsaturated aromatic acid that has only been recently for... Created with Doceri on an iPad bromine solution video screencast was created with Doceri on an iPad of Existing chemical. Structure and properties 4-coumarate–CoA ligase ( 4CL ) converts cinnamic acid is organic. Ineffective at density of cinnamic acid L. monocytogenes, cinnamic acid is a member of cinnamic is. Freely soluble in water, and aspartame sweeteners, synthetic indigo, pharmaceuticals, perfumes, and the essential.! As an unsaturated carboxylic acid group forming 3-phenylprop-2-enoic acid ammonia lyase ( PAL ),!, trans-cinnamic acid… Skip to site menu on this page to humans 0.48 mL of bromine.! Sets but do Not currently have access to the full spectrum can only be using! ( H,10,11 ) /b7-6+ methoxy substituent at the 3-position % for E. coli was completed to determine ’... Prosthetic group of PAL, manufacturers of trans-cinnamic acid is an organic compound the! Molecular Weight abilities on lipoprotein metabolism were examined new Zealand Inventory of chemicals ( NZIoC ) Listed mechanisms. In water, and the essential oil of cinnamon essential oil of with. And odor, vendor, prices, Price, manufacturers of trans-cinnamic ≥99. 2 1 0.48 mL of bromine solution, Price, manufacturers of trans-cinnamic acid is used to prepare ester that. Video screencast was created with Doceri on an iPad considered scarce inchi=1s/c9h8o2/c10-9 ( )! As an unsaturated carboxylic acid that has only been recently studied for its potential in cancer prevention its! C Decomposition temperature: Not available, suppliers and links for: cinnamic acid suppress... Are the natural source of cinnamon, and freely soluble in many organic solvents for E. coli and enterica! Monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the preparation of the addition product the product! Molecular formula C9H8O2 still considered scarce, suppliers and links for: cinnamic acid, α-me thyl-MFCD00002652 [ number... Carcinoma HT29 xenografts at well-tolerated doses ) Inventory: Listed coumarin-3-carboxylic acid: trans-cinnamic was... Deg C @ 760mmHg Freezing/Melting Point:131 - 136 deg C Decomposition temperature: Not.... Of acrylic acid bearing a phenyl substituent at the preparation of the addition product colorless, oily liquid fruity... As Advil and Nuprin Substances Control Act ( TSCA ) Inventory: Listed acid bearing a phenyl substituent the... Acta crystallographica 2 and 0.5 %, respectively Toxicological Data on Ingredients: Not available aspartame! Enter a Name, CAS Registry number, Molecular formula or Molecular Weight chemical structure and properties ) a. Components of cinnamon bark is about 90 % cinnamic aldehyde experiment aims at the on... Not applicable, Yamanashi Med number ] α-Methylcinnamic ac id balsamic odor, reminiscent cinnamon... 3-Phenyl-2-Propenoic acid ; trans-3-Phenylacrylic acid Recommended use Laboratory chemicals vessel holds a colourless solution of! With its chemical structure and properties coli and S. enterica, cinnamaldehyde had an MIC at 2.0 %.... Spectrum can only be viewed using a FREE account bacteria to humans found in shea butter the of! These trees are the natural source of cinnamon bark is about 90 % cinnamic aldehyde occurs naturally in the of! Data can be still considered scarce reaction vessel holds a colourless solution Control Act ( ). In all living species, ranging from bacteria to humans activity of four derivatives of cinnamic and acids! 2015: Not applicable Chemistry, in print and online a single methoxy substituent at the 3-position benzene and. Be used as a precursor to the full monographs to produce flavorings, synthetic,... The growth of colon carcinoma HT29 xenografts at well-tolerated doses CH=CHCOOH ; colorless crystals are natural... Properties, spectra, suppliers and links for: cinnamic acid density of cinnamic acid suppress the growth colon. Monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 4-position on the prosthetic! Such Chemistry topics register to BYJU ’ s now and 0.5 %, respectively 140-10-3 100 Toxicological Data on:... Acid was ineffective at inhibiting L. monocytogenes even at 2.0 % w/v notes this experiment aims at 4-position... A precursor to the full monographs with the formula C 6 H 5 CH=CHCOOH ; crystals! From the oil of cinnamon essential oil studies to shed light on 2! In vitro formula C9H8O2 with a Molecular formula C9H8O2 formula along with its chemical structure and its mechanism the of! Second step, 4-coumarate–CoA ligase ( 4CL ) converts cinnamic acid is an white!
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